leukotriene c4 การใช้

In 1997 he received first prize of " The Lancet " for the paper reporting on genetic polymorphism of leukotriene C4 syntase.
This formation of hepoxilin A3-C appears analogous to the formation of leukotriene C4 by the conjugation of glutathione to leukotriene A4.
However, their production is stimulated in human eosinophils by physiological agonists such as prostaglandin D2, leukotriene C4, and interleukin 5.
A trimer of Leukotriene C4 synthase is localized on the outer nuclear membrane and endoplasmic reticulum, where it forms a complex with 5-Lipoxygenase-activating protein.
The protein encoded by this gene, LTC4S ( or "'glutathione S-transferase II "') is an enzyme that converts leukotriene A4 and glutathione to create leukotriene C4.